Selected Publications

 

Q. I. Churches, H. E. Stewart, S. B. Cohen, A. Shroder, P. Turner and C. A. Hutton, "Stereoselectivity of the Petasis Reaction with Various Chiral Amines and Styrenylboronic Acids" Pure Appl. Chem., 2008, 80, 687-694.

http://dx.doi.org/10.1351/pac200880040687

 

V. Mitsakos, R. C. J. Dobson, F. G. Pearce, S. R. Devenish, G. L. Evans, B. R. Burgess, M. A. Perugini, J. A. Gerrard and C. A. Hutton, "Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens?" Bioorg. Med. Chem. Lett., 2008, 18, 842-844.

http://dx.doi.org/10.1016/j.bmcl.2007.11.026

 

B. A. Boughton, R. C. J. Dobson, J. A. Gerrard and C. A. Hutton, "Conformationally constrained diketopimelic acid analogues as inhibitors of dihydrodipicolinate synthase," Bioorg. Med. Chem. Lett., 2008, 18, 460-463.

http://dx.doi.org/10.1016/j.bmcl.2007.11.108

 

P. F. Kaiser, Q. I. Churches and C. A. Hutton, "Organoboron reagents in the preparation of functionalised a-amino acids," Aust. J. Chem., 2007, 60, 799-810.

http://dx.doi.org/10.1071/CH07103

 

E. C. Shuter, H. Duong, C. A. Hutton and M. D. McLeod, "The enantioselective synthesis of APTO and AETD: polyhydroxylated-b-amino acid constituents of the microsclerodermin cyclic peptides," Org. Biomol. Chem., 2007, 5, 3183-3189.

http://dx.doi.org/10.1039/b707891a

 

C. A. Hutton and P. A. Bartlett, "Preparation of diaza[4.3.0]bicyclononene-based peptidomimetics," J. Org. Chem., 2007, 72, 6865-6872.

http://dx.doi.org/10.1021/jo071074x

C. A. Hutton,  M. A. Perugini and J. A. Gerrard, "Inhibition of lysine biosynthesis: an evolving antibiotic strategy" Mol. BioSyst., 2007, 3, 458-465.

http://dx.doi.org/10.1039/b705624a

J. A. Gerrard, C. A. Hutton and M. A. Perugini, "Inhibiting protein-protein interactions as an emerging paradigm for drug discovery," Mini Rev. Med. Chem. 2007, 7, 151-157.

A. K. L. Yuen, K. A. Jolliffe and C. A. Hutton, "Preparation of the Central Tryptophan Moiety of the Celogentin/Moroidin Family of Anti-mitotic Cyclic Peptides," Aust. J. Chem., 2006, 59, 819-826.

http://dx.doi.org/10.1071/CH06324

 

A. K. L. Yuen and C. A. Hutton, "Preparation of Cyclic Peptide Alkaloids Containing Functionalised Tryptophan Residues," Nat. Prod. Comm., 2006, 1, 907-919.

 

K. M. Soapi and C. A. Hutton, "Preparation of b-nitroalanine using the Easton three-component coupling method," Amino Acids, 2006, 31, 337-339.

http://dx.doi.org/10.1007/s00726-006-0261-x

T. J. Southwood, M. C. Curry and C. A. Hutton, "Factors affecting the efficiency and stereoselectivity of
a-amino acid synthesis by the Petasis reaction," Tetrahedron, 2006, 62, 236-242.

http://dx.doi.org/10.1016/j.tet.2005.09.114

A. K. L. Yuen and C. A. Hutton, "Deprotection of pinacolyl boronate esters via hydrolysis of intermediate potassium trifluoroborates," Tetrahedron Lett.
, 2005, 46, 7899-7903.

http://dx.doi.org/10.1016/j.tetlet.2005.09.101

O. Skaff, K. A. Jolliffe and C. A. Hutton, "Synthesis of the side-chain cross-linked tyrosine oligomers dityrosine, trityrosine and pulcherosine," J. Org. Chem.
, 2005, 70, 7353-7363.

http://dx.doi.org/10.1021/jo051076m

 

L. Hunter, M. D. McLeod and C. A. Hutton, "Synthesis of the b-Hydroxydopa-g-hydroxy-d-sulfinylnorvaline Component of Ustiloxins A & B," Org. Biomol. Chem., 2005, 3, 732-734.

http://dx.doi.org/10.1039/b418876d

 

J. J. Turner, J. A. Gerrard and C. A. Hutton, "Heterocyclic Inhibitors of Dihydrodipicolinate Synthase are Not Competitive," Bioorg. Med. Chem., 2005, 13, 2133-2140.

http://dx.doi.org/10.1016/j.bmc.2005.01.001

 

J. J. Turner, J. P. Healy, R. C. J. Dobson, J. A. Gerrard and C. A. Hutton, "Two new irreversible inhibitors of dihydrodipicolinate synthase: diethyl (E,E)-4-oxo-2,5-heptadienedioate and diethyl (E)-4-oxo-2-heptenedioate," Bioorg. Med. Chem. Lett., 2005, 15, 995-998.

http://dx.doi.org/10.1016/j.bmcl.2004.12.043

 

T. E. Pennington, C. Kardiman and C. A. Hutton, "Deprotection of pinacolyl boronate esters by transesterification with polystyrene-boronic acid," Tetrahedron Lett., 2004, 45, 6657-6660.

http://dx.doi.org/10.1016/j.tetlet.2004.07.014

 

L. Hunter and C. A. Hutton, "Preparation of Selectively Protected L-Dopa Derivatives: Oxidation of Tyrosine-3-boronates," Aust. J. Chem., 2003, 56, 1095-1098.

http://dx.doi.org/10.1071/CH03181

 

C. A. Hutton and O. Skaff, "A Convenient Preparation of Dityrosine via Miyaura Borylation-Suzuki Coupling of Iodotyrosine Derivatives," Tetrahedron Lett., 2003, 44, 4895-4898.

http://dx.doi.org/10.1016/S0040-4039(03)01081-5

 

C. A. Hutton, T. J. Southwood and J. J. Turner, "Inhibitors of Lysine Biosynthesis as Antibacterial Agents," Mini Reviews Med. Chem. 2003, 3, 115-128.