2010
(55) McGill, N.W., Williams, S.J., ‘2,6-Disubstituted
benzoates as neighboring groups for enhanced diastereoselectivity
in b-galactosylation reactions:
Synthesis of b-1,3-linked
oligogalactosides related to arabinogalactan proteins’, J. Org. Chem., accepted 12 Nov 2009.
2009
(54) Zammit, S.C., Cox, A.J., Gow,
R.M., Zhang, Y., Gilbert, R.E., Krum, H., Kelly, D.J., Williams, S.J., ‘Evaluation
and optimization of antifibrotic activity of cinnamoyl anthranilates’, Bioorg. Med. Chem. Lett.,
2009, 19, 7003-7006.
(53) Goodger, J.Q.D., Cao, B., Jayadi,
(52)
(51) Bojarová,
P., Williams, S.J., ‘Aryl sulfamates are broad
spectrum inactivators of sulfatases: Effects on
sulfatases from various sources’, Bioorg. Med. Chem. Lett., 2009, 19, 477-480. [link]
(50) Loft, K.J., Bojarová,
P., Slámová, K., Křen,
V., Williams, S.J., ‘Synthesis of sulfated glucosaminides
for profiling substrate specificities of sulfatases and fungal b-N-acetylhexosaminidases’, ChemBioChem, 2009, 10,
565-576. [link]
(49) Williams,
S.J., 'Glycoconjugate Structure and
Biosynthesis', in 'Wiley Encyclopedia of Chemical Biology', Ed. Begley, T.P.,
2009, 4 volumes, 3188 pages, 260 chapters, John Wiley and Sons, pp1-14,. ISBN:
978-0-471-75477-0. [link].
(48) Stick, R.V., and Williams, S.J., ‘Carbohydrates. The Essential Molecules of Life', 2009,
474 pages, ISBN 978-0-240-52118-3, Elsevier,
2008
(47) Watt, J.A., Gannon, C.T.,
Loft, K.J., Dinev, Z., and Williams, S.J., ‘“Click”
preparation of carbohydrate 1-benzotriazoles, 1,4-disubstituted
and 1,4,5-trisubstituted triazoles and their utility
as glycosyl donors’, Aust. J. Chem.,
2008, 61, 837-846. [link]
(46)
(45) Bojarová, P., and Williams, S.J., 'Sulfotransferases,
sulfatases and formylglycine-generating enzymes: a sulfation
fascination', Curr. Opin. Chem. Biol., 2008, 12, 573-581. [link]
(44) McGill, N., and Williams, S.J., 'Anhydro sugars' in .Glycoscience: Chemistry and Chemical Biology', Ed.
Fraser-Reid, B.O., Tatsuta, K., Thiem, J., Coté, G.L., Flitsch, S., Ito, Y.,
Kondo, H., Nishimura, S.-i., Yu, B., 2nd
Ed, 2008, Vol. I, Springer:
(43) Bojarova, P., Denehy, E., Walker,
I., Loft, K., De Souza, D.P., Woo, L.W., Potter, B.V.L., McConville,
M.J., Williams, S.J., ‘Direct Evidence for ArO-S
Bond Cleavage upon Inactivation of Pseudomonas
aeruginosa Arylsulfatase
by Aryl Sulfamates’, ChemBioChem, 2008, 9,
613-623. [link]
(42) Qin,
C., Chen, X., Hughes, R.A., Williams, S.J., Woodman, O.L.,
‘Understanding the cardioprotective effects of
flavonols: Discovery of relaxant flavonols without antioxidant activity’, J. Med. Chem., 2008, 51,
1874-1884. [link]
(41) Donnelly,
P.S.,
2007
(40) Dinev, Z., Gannon, C. T., Egan, C., Watt, J.
A., McConville, M. J. and Williams, S. J.,
'Galactose-derived phosphonate analogues as potential inhibitors of
phosphatidylinositol biosynthesis in mycobacteria', Org. Biomol. Chem., 2007, 5,
952-959. [link]
(39) Senaratne, R.H., Mougous, J.D., Reader, J.R., Williams, S.J., Zhang,
T., Bertozzi, C.R. and Riley, L.W., 'Vaccine efficacy
of attenuated but persistent Mycobacterium
tuberculosis cysH mutant', J. Med. Microbiol., 2007, 56,
454-458. [link]
(38) Wicki, J., Williams,
S.J., Withers, S.G., ‘Transition-State Mimicry by Glycosidase Inhibitors: A
Critical Kinetic Analysis’, J. Am. Chem.
Soc., 2007, 129, 4530-4531. [link]
(37) Denehy, E., White, J.M., Williams, S.J., ‘The electronic structure of the sulfonyl
and phosphonyl groups: A computational and
crystallographic study’, Inorg. Chem., 2007, 46, 8871-8886. [link]
(36) Loft, K. and Williams, S.J., 'Complex carbohydrate
modifying enzymes' in 'Glycobiology', Ed. C. Sansom and O. Markman. 2007,
pp.202-216, Scion: Bloxham:
2006
(35) Denehy, E., White,
J.M., and Williams, S.J., ‘Ground state structures of sulfate monoesters and sulfamates
reveal similar reaction coordinates for sulfuryl and sulfamyl transfer’, Chem.
Commun., 2006, 314-316. [link]
(34) Williams,
S.J., Hekmat, O., and Withers, S.G.,
‘Synthesis and testing of mechanism-based protein profiling probes for
retaining endo-glycosidases’, ChemBioChem, 2006, 7, 116-124.
[link]
(33) Senaratne, R.H., De Silva, D., Williams, S.J., Mougous, J.D., Reader, J.R., Zhang, T., Chan, S., Sidders, B., Lee, D.H., Chan, J., Bertozzi,
C.R., Riley, L.W., ‘5’-Adenosinephosphosulfate reductase (CysH)
protects Mycobacterium tuberculosis
against free radicals during chronic infection phase in mice’, Mol. Microbiol.,
2006, 59, 1744-1753. [link]
(32) Dinev, Z., Wardak,
A.Z., Brownlee, R.T.C., and Williams, S.J., ‘A convenient gram-scale
synthesis of uridine diphospho(13C6)glucose’
Carbohydr. Res., 2006, 341, 1743-1747. [link]
(31) Sernee, F. M., Ralton, J. E., Dinev, Z., Khairallah, G. N., O'Hair, R. A.
J., Williams, S. J. and McConville, M. J.,
‘Biosynthesis of Leishmania mannan is
primed by a novel mannose-cyclic phosphate’, Proc. Natl. Acad. Sci., 2006, 103, 9458-9463. [link]
(30) van der Peet, P., Gannon, C.T., Walker, I., Dinev, Z., Angelin, M., Tam, S., Ralton,
J.E., McConville, M.J., and Williams, S.J.,
‘Use of click chemistry to define the substrate specificity of Leishmania b-1,2-mannosyltransferases’, ChemBioChem,
2006, 7, 1384-1391. [link]
2005
(29) Watt, J.A., and Williams,
S.J., ‘Rapid, iterative assembly of octyl a-1,6-oligomannosides and their 6-deoxy equivalents’, Org. Biomol. Chem., 3. 2005, 1982-1992. [link]
(28) Y. S. Morita, R. Velasquez, E. Taig, R.
F. Waller, J. H. Patterson, D. Tull, S. J. Williams, H. Billman-Jacobe,
and M. J. McConville,, ‘Compartmentalization of lipid
biosynthesis in mycobacteria’ J. Biol. Chem., 2005, 280, 21645-21652. [link]
(27) Hekmat, O., Kim, Y-W., Williams, S.J., He, S., and Withers, S.G., ‘Active-site
peptide ‘fingerprinting’ of glycosidases in complex
mixtures by mass spectrometry: Discovery of a previously undiscovered retaining b-1,4-glycanase
in Cellulomonas fimi’, J.
Biol. Chem., 2005, 280, 35126-35135. [link]
(26) Williams, S.J. ‘Trifluoromethanesulfonic anhydride’
in ‘Handbook of Reagents for Organic Synthesis: Reagents for Glycoside,
Nucleotide, and Peptide Synthesis’, Ed. Crich, D.,
2005, pp. 634-642, John Wiley and Sons:
2004
(25) Woodruff, P.J., Carlson, B.L., Siridechadilok,
B., Pratt, M.R., Williams, S.J., Bertozzi C.R., ‘Trehalose is
required for growth of Mycobacterium
smegmatis’ J. Biol. Chem. 2004, 279, 28835-28843. [link]
(24) Gloster, T., Williams, S.J., Roberts, S.,
2003
(23) Gloster, T., Williams, S.J., Tarling, C., Roberts, S., Dupont,
C., Jodoin, P., Shareck, F., Withers, S.G., and Davies, G.J., ‘A xylobiose-derived isofagomine lactam glycosidase
inhibitor binds as its amide tautomer’ Chem. Commun.,
2003, 944-945. [link]
(22) Williams, S.J., and Best, J.D., ‘Novel
microsomal triglyceride transfer
protein inhibitors’ Expert Opin. Therapeutic Pat., 2003, 13, 479-488.
2002
(21) Notenboom, V., Boraston, A.B. Williams, S.J., Kilburn, D.G., and
Rose, D.R.; ‘High-resolution crystal structures of the lectin-like xylan binding domain from Streptomyces lividans Xylanase
10A with bound substrates reveal a novel mode of xylan
binding’, Biochemistry, 2002, 41, 4246-4254. [link]
(20) Williams, S.J., and Withers, S.G., ‘Glycosynthases: Mutant glycosidases
for glycoside synthesis’, Aust. J. Chem., 2002, 55,
3-12.
(19) Mougous, J.D., Green, R.E., Williams, S.J., Brenner, S.E., and Bertozzi,
C.R., ‘Sulfotransferases and sulfatases in
mycobacteria’, Chemistry and Biology,
2002, 9, 767-776. [link]
(18) Williams, S.J., Senaratne,
R.H., Mougous, J.D., Riley, L., and Bertozzi, C.R., ‘5’-Adenosinephosphosulfate lies at a
metabolic branchpoint in mycobacteria’, J. Biol. Chem., 2002, 277, 32606-32615. [link]
(17) Williams, S.J., Mark, B., Vocadlo,
D.J., James, M.N.G., and Withers, S.G., ‘Aspartate
313 in the Streptomyces plicatus hexosaminidase plays a critical role in substrate assisted
catalysis by orienting the 2-acetamido group and stabilizing the transition
state’, J. Biol. Chem., 2002, 277, 40055-40065. [link]
(16) Mougous, J.D., Leavell,
M.D., Senaratne, R.H., Leigh, C.D., Williams, S.J., Riley, L.W., Leary, J.A.,
and Bertozzi, C.R., ‘Discovery of sulfated
metabolites in mycobacteria with a genetic and mass spectrometric approach’, Proc. Natl. Acad. Sci. USA, 2002, 99, 17037-17042. [link]
2001
(15) Stick, R.V., and Williams, S.J., ‘Anomeric Anhydro Sugars’, ‘Glycoscience:
Chemistry and Chemical Biology’, Ed. Fraser-Reid,
B.O., Tatsuta, K., and Thiem, J., 2001, Vol. I, 627-642, Springer-Verlag:
Heidelberg.
(14) Williams, S.J., and Davies, G.J.,
‘Protein-carbohydrate interactions: Learning lessons from nature’, Trends in Biotechnology, 2001, 19, 356-362. [link]
2000
(13) Skelton,
B., Stick, R.V., Tilbrook, D.M.G., White, A.H., and Williams, S.J., ‘Investigations into
the chemistry of some 1,6-Epithio- and 1,6-episeleno-b-D-glucopyranoses’, Aust. J. Chem.,
2000, 53, 389-397.
(12) Williams, S.J., Hoos,
R., and Withers, S.G., ‘Nanomolar versus millimolar inhibition by xylobiose-derived
azasugars: Significant differences between two
structurally distinct xylanases’, J. Am. Chem. Soc., 2000, 122, 2223-2235. [link]
(11) Williams, S.J., Notenboom,
V., Wicki, J., Rose, D.R., and Withers, S.G., ‘A new,
simple, high affinity glycosidase inhibitor: analysis of binding through X-ray
crystallography, mutagenesis and kinetic analysis’, J. Am. Chem. Soc., 2000, 122,
4229-4230. [link]
(10) Notenboom, V., Williams,
S.J., Hoos, R., Withers, S.G., and Rose, D.R.,
‘Detailed structural analysis of glycosidase/inhibitor interactions: complexes
of Cex from Cellulomonas fimi with xylobiose-derived aza-sugars’, Biochemistry,
2000, 39, 11553-11563. [link]
(9) Williams, S.J., and Withers, S.G.,
‘Glycosyl fluorides in enzymatic reactions’, Carbohydr. Res., 2000, 327,
27-46. [link]
1995-1999
(8) Stick,
R.V., Tilbrook, D.M.G., and Williams, S.J., ‘b-Acarbose VIII: The
synthesis of some N-linked carba-oligosaccharides’, Aust. J. Chem., 1999, 52, 895-904.
(7) Stick,
R.V., Tilbrook, D.M.G., and Williams, S.J., ‘b-Acarbose
(6) Stick,
R.V., Tilbrook, D.M.G., and Williams, S.J., ‘1,6-Epithio- and
1,6-episeleno-b-D-glucopyranose: Useful adjuncts in the synthesis of 6-deoxy-b-D-glucosides’, Aust. J. Chem., 1999, 52, 685-693.
(5) Stick, R.V., Tilbrook, D.M.G., and Williams,
S.J., ‘The synthesis of some seleno- and telluro-b-D-glucopyranosides’,
Aust. J. Chem,
1997, 50, 233-235.
(4) Stick, R.V., Tilbrook, D.M.G., and Williams, S.J., ‘The
selective activation of telluro- over seleno-b-D-glucopyranosides
as glycosyl donors: An activity scale for various telluro-,
seleno- and thio-sugars’, Aust. J. Chem, 1997, 50, 237-240.
(3) Stick, R.V., Tilbrook, D.M.G., and Williams, S.J., ‘1,6-Epithio-
and 1,6-episeleno-b-D-glucopyranose: Useful adjuncts in the synthesis of 6-deoxy-b-D-glucosides’, Tetrahedron Lett.,
1997, 38, 2741-2744.
(2) Bouchet, F., Driguez, H., McAuliffe, J.C., Stick, R.V., Tilbrook, D.M.G., and Williams
S.J., ‘A new approach to some 1,6-dideoxy-1,6-epithio
sugars’, Aust. J. Chem., 1996, 49, 343-348.
(1) Brunow, G., Stick,
R.V., Syrjänen, K., Tilbrook,
D.M.G., and Williams S.J., ‘A
synthesis of (Z)-9-octadecene-1,18-dioic acid’, Aust.
J. Chem., 1995, 48, 1893-1897.
Patents
(1) Bertozzi,
C.R., Williams, S.J., Mougous, J.D.
‘Mycobacterial sulfation pathway proteins and methods
of use thereof’, PCT Int. Appl. (2003), US 2003180321.
(2)
(3) Zammit, S., Williams, S.J.
and Kelly, D. J., 'New antifibrotic agents', AU PCT (2007), AU 004988753.
(4) Jarrott, B., Zanatta,
S.D., and Williams, S.J., 'Dithiole compounds as Cox inhibitors' WO 2008052288,
A1 20080508, PCT Int. Appl. (2008).
(5) Kelly,
D.J., Williams, S.J., Zammit, S.,
Halogenated cinnamoylbenzamide
analogs of anti-fibrotic agents and their preparation’, PCT Int. Appl.
(2009), WO 2009079692, A1
20090702.
Book Reviews
(6) Williams,
S.J., and Withers, S.G., ‘Essentials of carbohydrate chemistry and
biochemistry’ by Thisbe Lindhorst’,
Book Review, Angew. Chem. Int. Ed., 2000, 39,
3143-3144.
(7) Williams, S.J.
‘Peptides and proteins’ by Shawn Doonan, Book Review,
Aust. J. Chem., 2003, 56, 839.
Commentaries and Essays
(8) Williams,
S.J., Davies, G.J. ‘A master of its sulfate’, Nature Struct. Mol. Biol., 2004, 11, 686-687. Commentary for
‘Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis’. [link]
(9) Williams,
S.J., ‘Robert Vyent Stick: A Colourful
Character’, Aust. J. Chem. 2009, 62,
503-509.